Testicular Development in the Unilaterally Cryptorchid Rat

Testicular Volume and Testicular Atrophy Index as Predictors of Functionality of Unilaterally Cryptorchid Testis

GOAL The goal of this study was to determine relationship between the sensitivity and specificity of testicular volume (TV) and testicular atrophy index (TAI) in the indirect assessment of functional ability of cryptorchid testicles. MATERIAL AND METHODS The study included sixty children with unilateral cryptorchidism who were treated surgically at the Clinic of Pediatric Surgery, Clinical Ce...

Histological testicular parameters in bilateral cryptorchid adult rams

Testicular gene expression in cryptorchid boys at risk of azoospermia.

Despite timely and successful surgery, 32% of patients with bilateral and 10% with unilateral cryptorchidism will develop azoospermia. Cryptorchid boys at risk of azoospermia display a typical testicular histology of impaired mini-puberty at the time of the orchidopexy. During mini-puberty increased gonadotropin and testosterone secretion stimulate transformation of gonocytes into Ad spermatogo...

Testicular neoplasia in cryptorchid boys at primary surgery: case series.

Chobot (Poland); G Joner (Norway); D Michalkova (Slovakia); C Patterson (Northern Ireland); P Pozzilli (Italy, Lazio); AG Schranz (Malta); P Smail (Scotland); M Songini (Italy, Sardinia); B Urbonaite (Lithuania); E Wadsworth (British Paediatric Survey, UK). Funding: The European diabetes (EURODIAB) research network is supported by the European Commission medical research programme (contracts BM...

Ghrelin modulates testicular damage in a cryptorchid mouse model

Cryptorchidism or undescended testis (UDT) is a common congenital abnormality associated with increased risk for developing male infertility and testicular cancer. This study elucidated the effects of endogenous ghrelin or growth hormone secretagogue receptor (GHSR) deletion on mouse reproductive performance and evaluated the ability of ghrelin to prevent testicular damage in a surgical cryptor...